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Among them, protein kinase C (PKC), a family of protein kinase enzymes involved in various cellular mechanisms, has been shown to phosphorylate NRF2 at Ser40 in its Neh2 domain, disrupting the association with KEAP1 and promoting its activation [203, 204]

10.1002/osp4.124 15 Da PortoA.CasarsaV.ColussiG.CatenaC.CavarapeA.SechiL

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Alpha-lipoic acid also helps to combat free radicals in the body and is capable of regenerating other antioxidants such as vitamin C, vitamin E and glutathione